What is the CE-PRIME Research Study?
The purpose of this study is to determine if the use of ultrasound imaging and measuring cervical softness can help us better understand and predict preterm birth. This will allow us to develop better ways to prevent preterm birth in the future.
Why is this study important?
An estimated 13 million preterm births (PTBs) occur annually worldwide and PTBs are the single most significant contributing factor to neonatal morbidity and mortality. One of the biggest challenges we face is the inability to predict who will deliver preterm and who will not.
Your participation may help patients and babies for years to come.
Who qualifies for this study?
You may be able to participate in this study if you meet the following criteria:
- 18 years of age or older
- Less than 20 weeks pregnant
- This is your first pregnancy
- Singleton pregnancy (pregnant with only one child)
- No major fetal anomalies
What will I need to do if I participate in this study?
If you are eligible and agree to participate in this study, we will use a small ultrasound probe in the vagina to look at your cervix at three points during your pregnancy. We will schedule these visits at your convenience and will try to make them at the same time you are here for regular clinic or ultrasound visits, so it is easy for you.
These three time points are:
- 12-14.7 weeks
- 15-17.7 weeks
- 18-21.7 weeks
You will receive compensation of a $25 Amazon e-gift card after each completed visit.
How do I learn more about this study?
If you are interested in learning more about or participating in the CE-PRIME Research Study, please contact Amanda O’Neill, RN, BSN at 401-449-0794.
The CE-PRIME Trial- sponsored by the National Institute of Health (NIH)
Principal Investigators:
- Methodius Tuuli, MD, MPH, MBA
Executive Chief of Obstetrics and Gynecology
Women & Infants Hospital
Assistant Professor in the Division of Maternal-Fetal Medicine
The Warren Alpert Medical School of Brown University
Division Chief for Maternal-Fetal Medicine
Michigan Medicine
Asst. Professor, OBGYN
Washington University School of Medicine in St. Louis
Maternal-Fetal Medicine, Obstetrics & Gynecology
Washington University Physicians
Confidentiality: Your privacy is our priority. We have strict protocols in place to keep your information confidential.